Which bone graft material is osteogenic as well as osteoinductive and osteoconductive?

Which bone graft material is osteogenic as well as osteoinductive and osteoconductive?

• A. Autograft
• B. Allograft
• C. Xenograft
• D. Alloplast

Answer: (A)

Bone graft materials are classified by three properties: osteogenesis, osteoinduction, and osteoconduction. The material that is osteogenic provides living cells capable of forming new bone; osteoinductive materials contain factors that recruit and transform host cells into bone-forming cells; osteoconductive materials supply a scaffold for new bone to grow on. An autograft from the same patient brings all three: viable bone-forming cells, growth factors that induce bone formation, and a natural matrix that guides new bone growth. This combination makes autograft capable of forming new bone directly, recruiting host cells, and providing a structural framework. Other materials generally lack one of these components—processed allografts often lose viable cells (not osteogenic) but may be osteoinductive or osteoconductive; xenografts and many alloplasts mainly offer osteoconduction and are not osteogenic.

Bone graft materials are classified by three properties: osteogenesis, osteoinduction, and osteoconduction. The material that is osteogenic provides living cells capable of forming new bone; osteoinductive materials contain factors that recruit and transform host cells into bone-forming cells; osteoconductive materials supply a scaffold for new bone to grow on. An autograft from the same patient brings all three: viable bone-forming cells, growth factors that induce bone formation, and a natural matrix that guides new bone growth. This combination makes autograft capable of forming new bone directly, recruiting host cells, and providing a structural framework. Other materials generally lack one of these components—processed allografts often lose viable cells (not osteogenic) but may be osteoinductive or osteoconductive; xenografts and many alloplasts mainly offer osteoconduction and are not osteogenic.